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Treatment with bedaquiline significantly reduces mortality among South African patients with XDR- and MDR-TB
by Michael Carter, 2018-07-16 08:10
Bedaquiline-based regimens are associated with large reductions in mortality in patients with drug-resistant tuberculosis, according to research conducted in South Africa and published in Lancet Respiratory Diseases. Compared to standard regimens , use of bedaquiline reduced the risk of all cause mortality by 75% in patients with extensively drug-resistant tuberculosis (XDR-TB) and by 65% for patients

Treatment with bedaquiline significantly reduces mortality among South African people with XDR- and MDR-TB
by Michael Carter, 2018-07-16 08:10
Bedaquiline-based regimens are associated with large reductions in mortality in people with drug-resistant tuberculosis, according to research conducted in South Africa and published in The Lancet Respiratory Medicine. Compared to standard regimens, use of bedaquiline reduced the risk of all cause mortality by 75% in people with extensively drug-resistant tuberculosis (XDR-TB) and by 65% for

Will an HIV vaccine that protected two-thirds of monkeys do the same for humans?
by Gus Cairns, 2018-07-13 10:30
The Lancet last Friday published the 52-week results of APPROACH, an HIV vaccine whose 28-week results, reported by Aidsmap last year, were sufficiently impressive for it to be taken forward into a human efficacy trial among 2600 young women in southern Africa. These latest results provided more details of the immune responses to

PrEP@Home pilot shows monitoring PrEP without clinic visit is feasible and acceptable
by Keith Alcorn, 2018-07-12 08:20
A pilot project, PrEP@Home, reduced clinic visits to one a year and demonstrated that men who have sex with men in three US cities were able to carry out all necessary sampling for tests at home, finding the experience of using the PrEP@Home package acceptable, investigators report in the online

Does U=U for breastfeeding mothers and infants? Researchers highlight unanswered questions
by Keith Alcorn, 2018-07-11 08:10
Research is urgently needed to provide clear recommendations on breastfeeding to mothers with HIV who have an undetectable viral load on antiretroviral treatment, a group of researchers say in the journal Lancet HIV. They say that “There is insufficient evidence to state that U=U in the context of breastfeeding”. Although the

Online HIV prevention programme reduces STIs by 40% in young men who have sex with men
by Roger Pebody, 2018-07-10 10:40
An interactive online programme, tailored to real-life contexts of ethnically diverse young American men who have sex with men (MSM), resulted in a substantial drop in sexually transmitted infections (STIs) and a fall in condomless anal sex, according to the results of a randomised trial reported in the American Journal of Preventive Medicine. The Keep