Studies look at brain and cognitive changes in people with HIV as they age
People with HIV often show persistent signs of cognitive impairment and
abnormalities in brain structure despite suppressive antiretroviral therapy
(ART), but they do not appear to experience accelerated decline compared to
HIV-negative people as they age, according to research presented at the 2017 Conference
on Retroviruses and Opportunistic Infections (CROI) last month in Seattle.
HIV-associated neurocognitive disorder remains a poorly-understood
co-morbidity in HIV-positive people. While frank AIDS dementia is now rare among
people who receive effective antiretroviral treatment, more subtle cognitive
problems – some of which may only be revealed by specialised testing – remain
common. Cognitive decline is a concern as the HIV population ages; currently
more than half of people living with HIV in the US are over age 50.